Asset profile

GSK5784283

Monoclonal antibody

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Phase 3underway

Evidence outlook · registrational

Asthma: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2029-02-15.

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Competitive landscape

66 competitors in this universe: 4 direct rivals (same mechanism and indication), 2 same-class, 60 same-indication; 38 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
GSK5784283: this drugPhase 3Monoclonal antibodyTSLP
Tezepelumab (Tezspire)ApprovedMonoclonal antibodyTSLP, Thymic stromal lymphopoietin (TSLP), ligand-neutralizing
Tezepelumab (APFS)ApprovedMonoclonal antibodyTSLP
AZD8630Phase 2—TSLP
WIN378Phase 2Monoclonal antibodyTSLP
CM326Phase 3Monoclonal antibodyTSLP
BSI-045BPhase 2Monoclonal antibodyTSLP
Albuterol (Armstrong Albuterol HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol / Budesonide (Airsupra)ApprovedCombinationBeta-2 adrenergic receptor, Glucocorticoid receptor, Glucocorticoid receptor / Beta-2 adrenergic receptor
Albuterol HFA (Armstrong's)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol HFA (Proventil HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol Sulfate (Armstrong)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol Sulfate (Provenetil-HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
AminophyllineApprovedSmall moleculePhosphodiesterase (multi-subtype)
Beclomethasone (QVAR)ApprovedSmall moleculeGlucocorticoid receptor
Beclomethasone Dipropionate / Formoterol Fumarate / GlycopyrrolateApprovedSmall moleculeGlucocorticoid receptor / Beta-2 adrenergic receptor / Muscarinic M3 receptor (ICS/LABA/LAMA triple combination)

…and 51 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(7 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
April 2027 (1)
Phase 1AsthmaRecruiting
Est. primary completion 2027-04-13 · NCT07712393 · CT.gov ↗
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2029 (6)
February 2029 (1)
Phase 3AsthmaRecruiting
Est. primary completion 2029-02-15 · NCT07780643 · CT.gov ↗
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March 2029 (2)
Phase 3Nasal PolypsNot yet recruiting
Est. primary completion 2029-03-06 · NCT07782970 · CT.gov ↗
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Phase 3Nasal PolypsRecruiting
Est. primary completion 2029-03-06 · NCT07782957 · CT.gov ↗
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May 2029 (1)
Phase 3AsthmaRecruiting
Est. primary completion 2029-05-04 · NCT07782996 · CT.gov ↗
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July 2029 (2)
Phase 3Pulmonary Disease, Chronic ObstructiveRecruiting
Est. primary completion 2029-07-20 · NCT07780669 · CT.gov ↗
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Phase 3Pulmonary Disease, Chronic ObstructiveRecruiting
Est. primary completion 2029-07-20 · NCT07780656 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (6)
Phase 2 (1)
Phase 1 (1)