Asset profile

Extended-release tacrolimus (VI-0106)

Small molecule

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Phase 3underway

Evidence outlook · registrational

Registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2028-05-31.

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Competitive landscape

3 competitors in this universe: 0 direct rivals (same mechanism and indication), 3 same-class, 0 same-indication; 2 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Extended-Release Tacrolimus (VI-0106): this drugPhase 3Small moleculeCalcineurin
CyclosporineApproved—Calcineurin
Voclosporin (Lupkynis)ApprovedSmall moleculeCalcineurin, Cyclophilin A (leading to calcineurin inhibition)
Nanosomal TacrolimusPhase 2Small moleculeCalcineurin
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Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2028 (1)
May 2028 (1)
Phase 3Pulmonary Arterial Hypertension, Pulmonary Arterial Hypertension (PAH), Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH) …Not yet recruiting
Est. primary completion 2028-05-31 · NCT07612657 · CT.gov ↗
What to watch
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.