Asset profile

Enlonstobart

Monoclonal antibody

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Phase 3underway

Evidence outlook · registrational

Non-Small Cell Lung Cancer: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2027-09-30.

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Competitive landscape

83 competitors in this universe: 22 direct rivals (same mechanism and indication), 1 same-class, 60 same-indication; 61 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Enlonstobart: this drugPhase 3Monoclonal antibodyPD-1
CemiplimabApprovedMonoclonal antibodyPD-1
NivolumabApprovedMonoclonal antibodyPD-1
Opdivo QvantigApprovedMonoclonal antibodyPD-1
PembrolizumabApprovedMonoclonal antibodyPD-1
Pembrolizumab Berahyaluronidase AlfaApprovedMonoclonal antibodyPD-1
RetifanlimabApprovedMonoclonal antibodyPD-1
ToripalimabApprovedMonoclonal antibodyPD-1
Abp 234Phase 3Monoclonal antibodyPD-1
BalstilimabPhase 3Monoclonal antibodyPD-1
CamrelizumabPhase 3Monoclonal antibodyPD-1
CetrelimabPhase 3Monoclonal antibodyPD-1
CT-P51Phase 3Small moleculePD-1
DostarlimabPhase 3Monoclonal antibodyPD-1
MB12Phase 3Monoclonal antibodyPD-1
PenpulimabPhase 3Monoclonal antibodyPD-1

…and 68 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(17 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
November 2026 (1)
Phase 4Uterine Cervical NeoplasmsRecruiting
Est. primary completion 2026-11-01 · NCT07776821 · CT.gov ↗
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December 2026 (1)
Phase 1/2Relapsed or Refractory Peripheral T Cell LymphomaNot yet recruiting
Est. primary completion 2026-12-31 · NCT07288814 · CT.gov ↗
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2027 (5)
January 2027 (1)
Phase 1/2Advanced Solid TumorNot yet recruiting
Est. primary completion 2027-01-30 · NCT06132217 · CT.gov ↗
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April 2027 (1)
Phase 1/2Locally Advanced Unresectable Esophageal Squamous CarcinomaNot yet recruiting
Est. primary completion 2027-04 · NCT06136988 · CT.gov ↗
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September 2027 (1)
Phase 3Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2027-09-30 · NCT07633873 · CT.gov ↗
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December 2027 (2)
Phase 2Head and Neck Squamous Cell CarcinomaNot yet recruiting
Est. primary completion 2027-12-30 · NCT06989671 · CT.gov ↗
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Phase 2/3Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2027-12-31 · NCT07662811 · CT.gov ↗
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2028 (4)
April 2028 (1)
Phase 2Ovarian Cancer, Recurrent Ovarian CancerRecruiting
Est. primary completion 2028-04-30 · NCT07714668 · CT.gov ↗
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June 2028 (2)
Phase 1/2Advanced Hepatocellular Carcinoma (HCC)Not yet recruiting
Est. primary completion 2028-06-26 · NCT07282509 · CT.gov ↗
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Phase 2HER2-positive Gastric CancerNot yet recruiting
Est. primary completion 2028-06-30 · NCT06998771 · CT.gov ↗
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December 2028 (1)
Phase 1/2Advanced Solid TumorsNot yet recruiting
Est. primary completion 2028-12-31 · NCT07622225 · CT.gov ↗
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2029 (3)
February 2029 (1)
Phase 2LOCALLY ADVANCED CERVICAL CANCERSNot yet recruiting
Est. primary completion 2029-02-01 · NCT06981858 · CT.gov ↗
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September 2029 (1)
Phase 3Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2029-09-30 · NCT07672223 · CT.gov ↗
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December 2029 (1)
Phase 2/3Esophageal Squamous Cell CarcinomaNot yet recruiting
Est. primary completion 2029-12-30 · NCT07251062 · CT.gov ↗
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2030 (1)
March 2030 (1)
Phase 2Locally Recurrent Rectal CancerRecruiting
Est. primary completion 2030-03-09 · NCT07183865 · CT.gov ↗
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2031 (1)
February 2031 (1)
Phase 2/3Metastatic Colorectal Cancer (CRC), Liposomal Irinotecan, Second-LineNot yet recruiting
Est. primary completion 2031-02-28 · NCT07585279 · CT.gov ↗
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2032 (1)
June 2032 (1)
Phase 2/3HER2-positive Gastric CancerNot yet recruiting
Est. primary completion 2032-06-30 · NCT07332533 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (3)
Phase 2/3 (4)
Phase 2 (12)
Phase 1/2 (6)
Phase 1 (1)
Phase 4 (1)
Used as active comparator (1)
Appears in other studies (2)