Asset profile

Enbrel liquid

Protein / enzyme therapeutic

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Dormantno recent development

Evidence outlook

No registered development activity since 2013

Registered studies concluded by 2013, with no approval on record and no active or planned study on the registry since. No sponsor statement of discontinuation has been sourced, but the trial history should be read as archival rather than an active program.

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Competitive landscape

60 competitors in this universe: 1 direct rival (same mechanism and indication), 0 same-class, 59 same-indication; 25 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Enbrel Liquid: this drugPhase 3Protein / enzyme therapeuticTNF-alpha / TNF-beta (lymphotoxin-alpha)
Etanercept (Enbrel)ApprovedProtein / enzyme therapeuticTNF-alpha, TNF-alpha / TNF-beta (lymphotoxin-alpha)
Abatacept (Orencia)ApprovedProtein / enzyme therapeuticCD80/CD86 (CTLA-4-Ig), Selective T Cell Costimulation Modulator, CD80/CD86 (B7-1/B7-2) on antigen-presenting cells
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Adbm (Cyltezo)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Ryvk (Simlandi)Approved—TNF-alpha
Aldesleukin (Proleukin)ApprovedRecombinant Cytokine (il-2)Interleukin-2 receptor (IL-2R)
Anakinra (r-metHuIL-1ra)ApprovedProtein / enzyme therapeuticInterleukin-1 receptor (IL-1R), Interleukin-1 receptor type 1 (IL-1R1)
Baricitinib (Olumiant)ApprovedSmall moleculeJAK, JAK1/2
Certolizumab Pegol (Cimzia)ApprovedAntibody fragmentTNF-alpha
CT-P13 (Inflectra / Remsima)ApprovedMonoclonal antibodyTNF-alpha
CT-P47 (tocilizumab) (Avtozma)ApprovedMonoclonal antibodyIL-6R antagonist
DenosumabApprovedMonoclonal antibodyRANKL
Golimumab (Simponi)ApprovedMonoclonal antibodyTNF-alpha
HZT-501 (Duexis)ApprovedSmall moleculeCyclooxygenase (COX-1/COX-2) plus histamine H2 receptor
Infliximab (Remicade)ApprovedMonoclonal antibodyTNF-alpha

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Appears in other studies (1)