Asset profile

CKD-506

Unknown / undisclosed

Phase 2HDAC6 (Histone deacetylase 6)No recent registered activity
Partialsignal

Evidence outlook · lead readout

NCT04204603 · Rheumatoid Arthritis

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT04204603: The study was randomized, double-blind, and placebo-controlled, with 122 participants assigned to placebo or one of three CKD-506 doses. Its primary clinical endpoint was change in DAS28(CRP) at week 12, but no results or statistical comparison were posted, so whether the endpoint was met is unknown.

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