BIIB091

Evidence outlook · lead readout

NCT05798520 · Relapsing Forms of Multiple Sclerosis

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT05798520: The study randomized 127 participants and used quadruple blinding with active and matching-placebo comparator arms. Its primary outcomes included adverse events and new MRI lesions, but no results or statistical comparison have been posted, so the primary endpoint cannot be judged as met or missed.