Asset profile

AZD5462

Small molecule

Partialsignal

Evidence outlook · lead readout

NCT06299826 · Chronic Heart Failure

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT06299826: The study was randomized, double-blind, and placebo-controlled, with 375 participants across three AZD5462 dose groups and a placebo group. Its primary endpoint was a surrogate echocardiographic measure, and no primary-outcome results or statistical comparison are currently available.

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