Asset profile

AT278

Peptide

Partialsignal

Evidence outlook · lead readout

NCT05754424 · Diabetes Mellitus, Type 2

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT05754424: Every participant received AT278 and the active comparator insulin in random order, with neither participants nor staff knowing which was given at each visit, which is a solid design. But the trial measured a pharmacology lab readout rather than a real-world blood sugar or complication outcome, and results have not yet been posted.

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