Asset profile

AG2304R

Small molecule

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Phase 3underway

Evidence outlook · registrational

Atherosclerotic Cardiovascular Disease: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. No upcoming registrational readout date is posted to the registry. Check News for topline announcements.

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Competitive landscape

63 competitors in this universe: 3 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 18 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
AG2304R: this drugPhase 3Small moleculeHMG-CoA reductase / NPC1L1
MK0653A, Ezetimibe (+) SimvastatinPhase 3Small moleculeHMG-CoA reductase / NPC1L1
Atozet (ezetimibe / Atorvastatin)Not yet studiedSmall moleculeHMG-CoA reductase / NPC1L1
RosuvamibeNot yet studiedSmall moleculeHMG-CoA reductase / NPC1L1
Alirocumab (Praluent)ApprovedMonoclonal antibodyPCSK9
Bempedoic Acid (Nexletol)ApprovedSmall moleculeAdenosine Triphosphate-Citrate Lyase Inhibitor, ATP citrate lyase
Bempedoic Acid / EzetimibeApprovedSmall moleculeATP citrate lyase (ACLY, bempedoic acid) and NPC1L1 (ezetimibe)
Cangrelor (Kengreal)ApprovedSmall moleculeP2Y12 receptor
Colchicine (cardiovascular) (Lodoco)ApprovedSmall moleculeMicrotubule/inflammasome (tubulin)
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Dulaglutide (Trulicity)ApprovedPeptideGLP-1 receptor
Evolocumab (Repatha)ApprovedMonoclonal antibodyPCSK9
Icosapent Ethyl (Vascepa)ApprovedSmall moleculeOmega-3 fatty acid (EPA)
Inclisiran (Leqvio)ApprovedRNA / oligonucleotidePCSK9
Liraglutide (Saxenda / Victoza)ApprovedPeptideGLP-1 receptor
Lomitapide (Juxtapid)ApprovedSmall moleculeMTP

…and 48 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Appears in other studies (1)