Head-to-head evidence
LNK01001 vs LW402
Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.
Atopic Dermatitis
Shared mechanism: JAK1 · full Atopic Dermatitis pipeline
LNK01001
Developed by Lynk Pharmaceuticals
NCT06277245 · Phase 3 · completed
This was a randomized, quadruple-blind, placebo-controlled trial in 356 patients that measured EASI-75 skin clearance and Investigator's Global Assessment response at week 16, the standard efficacy measures for atopic dermatitis. Both the 12 mg and 24 mg doses produced large, statistically significant improvements over placebo on both endpoints.
Caveat: this result is taken from a company announcement or a news report of one, not from the trial registry or a peer-reviewed publication. Treat the figures as the sponsor's own statement, not as independently verified evidence.
LW402
Developed by Shanghai Longwood Biopharmaceuticals
NCT07186387 · Phase 2 · completed
The trial was randomized and quadruple-blind, used a placebo control, and enrolled 144 participants; its primary endpoint was a clinical disease-response measure (EASI-50). Because the primary comparison result is not available, the study provides well-designed but incomplete evidence rather than evidence of a confirmed favorable effect.
Next expected readout: March 2028 · NCT07370909 (registry estimate)
The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: LNK01001's landscape · LW402's landscape