Head-to-head evidence

Gosogliptin vs Henagliflozin

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Type 2 Diabetes

Shared mechanism: DPP-4 · full Type 2 Diabetes pipeline

Gosogliptin

Developed by SatRx

Phase 3 in Type 2 Diabetessmall molecule
Partial signal

NCT03088670 · Phase 3 · completed

The study used randomization and an active comparator, but it was open-label and its primary endpoint was change in HbA1c, a surrogate measure rather than a hard clinical outcome. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

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Henagliflozin

Developed by Jiangsu Hengrui Pharmaceuticals

Phase 3 in Type 2 Diabetessmall molecule
Reliable signal

NCT03159052 · Phase 3 · status unknown

This was a randomized, quadruple-blind, placebo-controlled trial (n=450). The primary endpoint, HbA1c change at 24 weeks, was clearly met: both the 5 mg and 10 mg doses reduced HbA1c significantly more than placebo (p<.001 for each).

Next expected readout: December 2026 · NCT06448130 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Gosogliptin's landscape · Henagliflozin's landscape