Head-to-head evidence

duvakitug vs MT-201

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Ulcerative Colitis

Shared mechanism: TL1A · full Ulcerative Colitis pipeline

duvakitug

Developed by Teva Pharmaceutical Industries and partners

Phase 3 in Ulcerative Colitismonoclonal antibody (IgG1-λ2)
Partial signal

NCT05499130 · Phase 2b · completed

Randomized, double-blind, placebo-controlled, with the high dose reaching significance (p=.003) and replicating in a Crohn's disease cohort. The low dose was only borderline (p=.050) and the sample size per arm was modest. A well-designed trial with a partial, dose-dependent result is capped at moderate rather than strong. Progressed to Phase 3.

Caveat: this result is taken from a company announcement or a news report of one, not from the trial registry or a peer-reviewed publication. Treat the figures as the sponsor's own statement, not as independently verified evidence.

Next expected readout: May 2028 · NCT07184996 (registry estimate)

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MT-201

Developed by Mirador Therapeutics

Phase 2 in Ulcerative Colitisbispecific antibody (anti-TL1A/IL-23)
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: April 2027 · NCT07113522 (registry estimate)

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Crohn's Disease

Shared mechanism: TL1A · full Crohn's Disease pipeline

duvakitug

Developed by Teva Pharmaceutical Industries and partners

Phase 3 in Crohn's Diseasemonoclonal antibody (IgG1-λ2)
Partial signal

NCT05499130 · Phase 2b · completed

Randomized, double-blind, placebo-controlled, with the high dose reaching significance (p=.003) and replicating in a Crohn's disease cohort. The low dose was only borderline (p=.050) and the sample size per arm was modest. A well-designed trial with a partial, dose-dependent result is capped at moderate rather than strong. Progressed to Phase 3.

Caveat: this result is taken from a company announcement or a news report of one, not from the trial registry or a peer-reviewed publication. Treat the figures as the sponsor's own statement, not as independently verified evidence.

Next expected readout: May 2029 · NCT07184931 (registry estimate)

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MT-201

Developed by Mirador Therapeutics

Phase 2 in Crohn's Diseasebispecific antibody (anti-TL1A/IL-23)
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: April 2027 · NCT07113522 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: duvakitug's landscape · MT-201's landscape