Mechanism
Cysteinyl leukotriene receptor 1 (CysLT1) / PDE3 / PDE4 / 5-lipoxygenase
Assets acting on this target.
- Class
- Multi-pathway anti-inflammatory/anti-fibrotic small molecule (leukotriene receptor antagonist + phosphodiesterase inhibitor)
- Pathway
- Blocks leukotriene D4 signaling and inhibits PDE3/PDE4 (raising intracellular cAMP), with upstream 5-LO suppression, reducing vascular/hepatic inflammation and fibrosis