Asset profile

SKB571 For

Antibody–drug conjugate

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

68 competitors in this universe: 8 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 62 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
SKB571 For: this drugPhase 2Antibody–drug conjugateEGFR x c-MET
AmivantamabApprovedMultispecific antibodyEGFR x c-MET
Rybrevant Faspro (amivantamab And Hyaluronidase-Lpuj)ApprovedMultispecific antibodyEGFR x c-MET
ALK202Phase 2Small moleculeEGFR x c-MET
EMB-01Phase 2Multispecific antibodyEGFR x c-MET
MCLA-129Phase 2Multispecific antibodyEGFR x c-MET
225Ac-FPI-2068Phase 1RadiopharmaceuticalEGFR x c-MET
AZD9592Phase 1Antibody–drug conjugateEGFR x c-MET
QLS5316Phase 1Small moleculeEGFR x c-MET
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK
Alymsys (bevacizumab-Maly)ApprovedMonoclonal antibodyVEGF-A
AtezolizumabApprovedMonoclonal antibodyPD-L1
BAT1706 (Avzivi)ApprovedMonoclonal antibodyVEGF-A
BAY2927088 (Hyrnuo)ApprovedSmall moleculeHER2 (ERBB2) exon 20 insertions and point mutations; also mutant-selective EGFR
BevacizumabApprovedMonoclonal antibodyVEGF-A, Vascular Endothelial Growth Factor Inhibitor

…and 53 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
June 2027 (1)
Phase 2Non-small Lung CancerRecruiting
Est. primary completion 2027-06-30 · NCT07308106 · CT.gov ↗
What to watch
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August 2027 (1)
Phase 2Gastrointestinal TumorsRecruiting
Est. primary completion 2027-08-31 · NCT07564466 · CT.gov ↗
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2028 (2)
January 2028 (1)
Phase 2Lung Cancer (Non-Small Cell)Recruiting
Est. primary completion 2028-01-19 · NCT07230405 · CT.gov ↗
What to watch
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December 2028 (1)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2028-12-31 · NCT07622186 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (4)
Appears in other studies (2)