Asset profile

Senicapoc

Unknown / undisclosed

Phase 3Mechanism not established
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Phase 3underway

Evidence outlook · registrational

Sickle Cell Disease: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. No upcoming registrational readout date is posted to the registry. Check News for topline announcements.

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Competitive landscape

16 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 16 same-indication; 9 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Senicapoc: this drugPhase 3——
Crizanlizumab-Tmca (Adakveo)ApprovedMonoclonal antibodyP-selectin
Exagamglogene Autotemcel (Casgevy)ApprovedGene therapy / editing—
Hydroxyurea (Droxia)Approved——
Hydroxyurea (Siklos)Approved——
Hydroxyurea (Xromi)Approved——
L-Glutamine (Endari)Approved—Amino Acid
Lovotibeglogene Autotemcel (Lyfgenia)ApprovedGene therapy / editing—
Mitapivat (Pyrukynd)Approved——
Voxelotor (Oxbryta)Approved——
Decitabine / Tetrahydrouridine (NDec)Phase 2—DNMT1 (DNA methyltransferase 1)
HBI-002Phase 2Small moleculeCarbon monoxide (CO)-based gas therapeutic; oral liquid CO formulation
ITU512Phase 1/2——
Nula-CelPhase 1/2Cell therapy—
DISC-3405Phase 1——
SCD-101Phase 1——

…and 1 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(3 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2028 (2)
November 2028 (1)
Phase 1GlioblastomaRecruiting
Est. primary completion 2028-11-01 · NCT07284069 · CT.gov ↗
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December 2028 (1)
Phase 2Pulmonary Fibrosis, Interstitial Lung Disease, Idiopathic Pulmonary FibrosisRecruiting
Est. primary completion 2028-12 · NCT06714123 · CT.gov ↗
What to watch
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2029 (1)
January 2029 (1)
Phase 2Sickle Cell DiseaseRecruiting
Est. primary completion 2029-01 · NCT07282210 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 2 (3)
Phase 1 (1)