Asset profile
Decitabine/Tetrahydrouridine (NDec)
Unknown / undisclosed
Evidence outlook
Completed readouts not yet graded
This drug has completed mid- or late-stage studies whose evidence has not yet been graded on this platform. Where a sponsor has not posted registry results, topline data typically arrives via company announcements; see News.
How the evidence outlook works ↗
Featured trials
The studies most instrumental to this drug's clinical progression, individually graded on design and result. Pick an indication; Research unlocks the trials, endpoints, key results and grades.
Competitive landscape
17 competitors in this universe: 0 direct rivals (same mechanism and indication), 1 same-class, 16 same-indication; 11 further along in development.
| Drug | Stage | Modality | Mechanism | Evidence signal | Reported efficacygraded featured trials |
|---|---|---|---|---|---|
| Decitabine / Tetrahydrouridine (NDec): this drug | Phase 2 | — | DNMT1 (DNA methyltransferase 1) | ||
| Azacitidine | Phase 3 | Small molecule | DNMT1 (DNA methyltransferase 1) | ||
| Crizanlizumab-Tmca (Adakveo) | Approved | Monoclonal antibody | P-selectin | ||
| Exagamglogene Autotemcel (Casgevy) | Approved | Gene therapy / editing | — | ||
| Hydroxyurea (Droxia) | Approved | — | — | ||
| Hydroxyurea (Siklos) | Approved | — | — | ||
| Hydroxyurea (Xromi) | Approved | — | — | ||
| L-Glutamine (Endari) | Approved | — | Amino Acid | ||
| Lovotibeglogene Autotemcel (Lyfgenia) | Approved | Gene therapy / editing | — | ||
| Mitapivat (Pyrukynd) | Approved | — | — | ||
| Voxelotor (Oxbryta) | Approved | — | — | ||
| Senicapoc | Phase 3 | — | — | ||
| HBI-002 | Phase 2 | Small molecule | Carbon monoxide (CO)-based gas therapeutic; oral liquid CO formulation | ||
| ITU512 | Phase 1/2 | — | — | ||
| Nula-Cel | Phase 1/2 | Cell therapy | — | ||
| DISC-3405 | Phase 1 | — | — |
…and 2 more. Research shows the complete landscape.
Unlock the full comparison
Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.
Upcoming events
No upcoming readouts on record for this asset.
All registered studies
Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.