Asset profile

salbutamol

Small molecule

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Partialdesign only

Evidence outlook · results not reported

NCT06154304 · Bronchial Asthma

The lead study's design has limits that temper confidence (see the rationale below), and its results have not been reported. This tier describes the design, not an outcome.

NCT06154304: The study randomized and double-blinded 120 participants and included both placebo and active Ventolin comparator products. Its primary endpoint was the physiologic PD20/FEV1 methacholine-challenge measure rather than a hard clinical outcome, and no primary endpoint results are available.

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Competitive landscape

85 competitors in this universe: 23 direct rivals (same mechanism and indication), 2 same-class, 60 same-indication; 43 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Salbutamol: this drugPhase 3Small moleculeBeta-2 adrenergic receptor
Albuterol (Armstrong Albuterol HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol / Budesonide (Airsupra)ApprovedCombinationBeta-2 adrenergic receptor, Glucocorticoid receptor, Glucocorticoid receptor / Beta-2 adrenergic receptor
Albuterol HFA (Armstrong's)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol HFA (Proventil HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol Sulfate (Armstrong)ApprovedSmall moleculeBeta-2 adrenergic receptor
Albuterol Sulfate (Provenetil-HFA)ApprovedSmall moleculeBeta-2 adrenergic receptor
Fluticasone Furoate / Umeclidinium / Vilanterol (Trelegy Ellipta)ApprovedSmall moleculeMuscarinic acetylcholine receptor (M3), Beta-2 adrenergic receptor, Glucocorticoid receptor, Glucocorticoid receptor / Beta-2 adrenergic receptor / Muscarinic M3 receptor (ICS/LABA/LAMA triple combination)
Fluticasone Furoate / VilanterolApprovedSmall moleculeBeta-2 adrenergic receptor, Glucocorticoid receptor, Glucocorticoid receptor / Beta-2 adrenergic receptor
Fluticasone Propionate / Salmeterol (Advair HFA)ApprovedCombinationGlucocorticoid receptor, Beta-2 adrenergic receptor, Glucocorticoid receptor / Beta-2 adrenergic receptor
OlodaterolApprovedSmall moleculeBeta-2 adrenergic receptor
Olodaterol / Tiotropium BromideApprovedSmall moleculeMuscarinic acetylcholine receptor (M3), Beta-2 adrenergic receptor
ProventilApprovedSmall moleculeBeta-2 adrenergic receptor
Salmeterol (DISKUS)Approved—Beta-2 adrenergic receptor
Umeclidinium / VilanterolApprovedSmall moleculeMuscarinic acetylcholine receptor (M3), Beta-2 adrenergic receptor
Albuterol (Ventolin)Phase 3Small moleculeBeta-2 adrenergic receptor

…and 70 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (3)
January 2027 (1)
Early phase / not applicableTTNNot yet recruiting
Est. primary completion 2027-01-01 · NCT07350421 · CT.gov ↗
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June 2027 (1)
Phase 3AsthmaActive not recruiting
Est. primary completion 2027-06-25 · NCT06473779 · CT.gov ↗
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December 2027 (1)
Early phase / not applicableLung Diseases, Cystic FibrosisActive not recruiting
Est. primary completion 2027-12-31 · NCT03522831 · CT.gov ↗
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2029 (1)
December 2029 (1)
Early phase / not applicableAsthmaRecruiting
Est. primary completion 2029-12-31 · NCT07037511 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (52)
Phase 2/3 (4)
Phase 2 (22)
Phase 1 (18)
Phase 4 (55)
Early phase / not applicable (46)
Used as active comparator (10)
Appears in other studies (22)