Asset profile

RP1

Biologic (subtype unspecified)

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

Also in development:Melanoma · Phase 2

How the evidence outlook works ↗

Competitive landscape

72 competitors in this universe: 5 direct rivals (same mechanism and indication), 3 same-class, 64 same-indication; 65 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
RP1: this drugPhase 2Biologic (subtype unspecified)No discrete molecular target
Olvimulogene NanivacirepvecPhase 3Oncolytic VirusNo discrete molecular target
LN-145Phase 2Cell therapyNo discrete molecular target
KB707Phase 1/2Gene therapy / editingNo discrete molecular target
SL-28Phase 1/2Biologic (subtype unspecified)No discrete molecular target
KB-GDT-01Phase 1Biologic (subtype unspecified)No discrete molecular target
ALF201Phase 2Cell therapyNo discrete molecular target
Adipose-Derived MSC Clusters (S.Biomedics)Phase 1/2Cell therapyNo discrete molecular target
BGC101Phase 1/2Cell therapyNo discrete molecular target
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK
Alymsys (bevacizumab-Maly)ApprovedMonoclonal antibodyVEGF-A
AmivantamabApprovedMultispecific antibodyEGFR x c-MET
AtezolizumabApprovedMonoclonal antibodyPD-L1
BAT1706 (Avzivi)ApprovedMonoclonal antibodyVEGF-A
BAY2927088 (Hyrnuo)ApprovedSmall moleculeHER2 (ERBB2) exon 20 insertions and point mutations; also mutant-selective EGFR

…and 57 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2028 (2)
March 2028 (1)
Phase 1MelanomaRecruiting
Est. primary completion 2028-03-31 · NCT06216938 · CT.gov ↗
What to watch
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June 2028 (1)
Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2028-06 · NCT03767348 · CT.gov ↗
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2029 (2)
July 2029 (1)
Phase 1/2Merkel Cell Carcinoma, Basal Cell Carcinoma, Locally Advanced Cutaneous Squamous Cell Carcinoma, CancerActive not recruiting
Est. primary completion 2029-07 · NCT04349436 · CT.gov ↗
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October 2029 (1)
Phase 2Angiosarcoma, Angiosarcoma, AdultRecruiting
Est. primary completion 2029-10-31 · NCT06898970 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (3)
Phase 1/2 (3)
Phase 1 (1)