Asset profile

Quemliclustat

Small molecule

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Phase 3underway

Evidence outlook · registrational

Pancreatic Ductal Adenocarcinoma: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2030-11-30.

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Competitive landscape

2 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 2 same-indication; 1 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Quemliclustat: this drugPhase 3Small moleculeCD73 (NT5E)
Daraxonrasib (Rasonque)ApprovedSmall moleculepan-RAS, RAS (pan-RAS, RAS-mutant tumors)
VS-7375Phase 2Small moleculeKRAS G12D
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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(8 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (3)
December 2026 (3)
Phase 2Biliary Tract Carcinoma, Cholangiocarcinoma, Bile Duct CancerActive not recruiting
Est. primary completion 2026-12 · NCT06048133 · CT.gov ↗
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Phase 1/2Pancreatic Ductal AdenocarcinomaRecruiting
Est. primary completion 2026-12-01 · NCT05688215 · CT.gov ↗
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Phase 2Oligometastatic Prostate CancerRecruiting
Est. primary completion 2026-12-01 · NCT05915442 · CT.gov ↗
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2027 (3)
January 2027 (1)
Phase 2Gastrointestinal Tract MalignanciesActive not recruiting
Est. primary completion 2027-01 · NCT05329766 · CT.gov ↗
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April 2027 (1)
Phase 2Pancreatic Ductal AdenocarcinomaRecruiting
Est. primary completion 2027-04 · NCT06048484 · CT.gov ↗
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December 2027 (1)
Phase 2Advanced Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-12 · NCT05676931 · CT.gov ↗
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2029 (1)
July 2029 (1)
Phase 1/2Locally Advanced Bladder Urothelial Carcinoma, Locally Advanced Renal Pelvis Urothelial Carcinoma …Recruiting
Est. primary completion 2029-07-16 · NCT07667335 · CT.gov ↗
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2030 (1)
November 2030 (1)
Phase 3Pancreatic Ductal AdenocarcinomaActive not recruiting
Est. primary completion 2030-11-30 · NCT06608927 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2 (5)
Phase 1/2 (4)
Phase 1 (4)