Asset profile

NRD135S.E1

Small molecule

Phase 2Mechanism not established
Partialsignal

Evidence outlook · lead readout

NCT05480228 · Painful Diabetic Neuropathy

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT05480228: The trial randomized 127 participants to NRD135S.E1 or placebo and used double-blind masking. Its primary pain endpoint was a clinical patient-reported measure, but no results are available to show whether the comparison met its prespecified objective.

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