Asset profile

Pirenzepine (topical)

Small molecule

Phase 3underway

Evidence outlook · registrational

HIV: registrational readout pending

Entered Phase 3 on partial signal mid-stage evidence. No upcoming registrational readout date is posted to the registry — check News for topline announcements.

NCT05005078: The study randomly assigned 16 participants to topical WST-057 or placebo, with Part A open-label and Part B double-blinded. Its primary endpoints were laboratory, vital-sign, ECG, and skin-safety measures rather than a hard clinical outcome, and no primary-endpoint results were posted; the small sample also limits the strength of the evidence.

Also in development:Diabetic Peripheral Neuropathic Pain · Phase 2

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