Asset profile

BMS-986435

Small molecule

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

How the evidence outlook works ↗

Competitive landscape

61 competitors in this universe: 1 direct rival (same mechanism and indication), 0 same-class, 60 same-indication; 38 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
BMS-986435: this drugPhase 2Small moleculeCardiac myosin (inhibitor)
Mavacamten (Camzyos)ApprovedSmall moleculeCardiac myosin (inhibitor)
Baxdrostat (Baxfendy)ApprovedSmall moleculeAldosterone synthase (CYP11B2)
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Empagliflozin (Jardiance)ApprovedSmall moleculeSGLT2
Ferric Carboxymaltose (Injectafer / Ferinject)ApprovedIron Complex (iv)Iron repletion
Ferric Derisomaltose (Monoferric / Monofer)ApprovedIron Complex (iv)Iron repletion
Finerenone (Kerendia)ApprovedSmall moleculeMineralocorticoid receptor
Furosemide (subcutaneous, scPharmaceuticals) (FUROSCIX)ApprovedSmall moleculeNKCC2
Furosemide (subcutaneous, SQ Innovation) (Lasix ONYU)ApprovedSmall moleculeNKCC2
Icodextrin (peritoneal Ultrafiltration) (Extraneal)ApprovedDevice Solution (peritoneal Dialysis)Peritoneal ultrafiltration
Isosorbide Dinitrate / Hydralazine (BiDil)ApprovedSmall moleculeHydralazine/isosorbide dinitrate (fixed combination)
Ivabradine (Corlanor)ApprovedSmall moleculeIf (funny) channel
Sacubitril / Valsartan (Entresto)ApprovedSmall moleculeNeprilysin + Angiotensin II receptor (dual)
Sotagliflozin (Inpefa)ApprovedSmall moleculeSGLT1/2 (dual)
Tolvaptan (Samsca / Jinarc)ApprovedSmall moleculeVasopressin V2 receptor

…and 46 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
December 2026 (2)
Phase 2Heart FailureActive not recruiting
Est. primary completion 2026-12-14 · NCT06122779 · CT.gov ↗
What to watch
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Phase 1Healthy VolunteersRecruiting
Est. primary completion 2026-12-17 · NCT07226817 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (2)
Phase 1 (7)