Asset profile

agenT-797

Cell therapy

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

Also in development:Multiple Myeloma · Phase 1

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Competitive landscape

62 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 62 same-indication; 52 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
agenT-797: this drugPhase 2Cell therapyInvariant TCR / NKG2D ligands (tumor cell recognition), no single defined myeloma antigen
Belantamab MafodotinApprovedAntibody–drug conjugateBCMA
BortezomibApprovedSmall moleculeProteasome
CarfilzomibApprovedSmall moleculeProteasome
Ciltacabtagene AutoleucelApprovedCell therapyBCMA
DaratumumabApprovedMonoclonal antibodyCD38
DenosumabApprovedMonoclonal antibodyRANKL
ElotuzumabApprovedMonoclonal antibodySLAMF7 (CS1/CD319)
ElranatamabApprovedMultispecific antibodyBCMA x CD3
Idecabtagene VicleucelApprovedCell therapyBCMA
IsatuximabApprovedMonoclonal antibodyCD38
IxazomibApprovedSmall moleculeProteasome
LenalidomideApprovedSmall moleculeCereblon E3 ubiquitin-ligase, Thalidomide Analog
LinvoseltamabApprovedMultispecific antibodyBCMA x CD3
Melphalan FlufenamideApprovedSmall moleculeDNA (alkylation), delivered via aminopeptidase-mediated intracellular activation
Melphalan Hydrochloride (Evomela)ApprovedSmall moleculeDNA (guanine N7 position)

…and 47 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
June 2027 (1)
Phase 2PneumoniaRecruiting
Est. primary completion 2027-06 · NCT07615010 · CT.gov ↗
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August 2027 (1)
Phase 2Gastric CancerActive not recruiting
Est. primary completion 2027-08-01 · NCT06251973 · CT.gov ↗
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2028 (1)
September 2028 (1)
Phase 2Colorectal Cancer MetastaticRecruiting
Est. primary completion 2028-09 · NCT07550088 · CT.gov ↗
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2029 (1)
October 2029 (1)
Phase 1Allogenic Stem Cell Transplantation, Myeloid Malignancies, Lymphoid Malignancies, Acute Myeloid Leukemia, Chronic Myeloid Leukemia …Not yet recruiting
Est. primary completion 2029-10 · NCT07758218 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (4)
Phase 1 (4)
Used as active comparator (1)