Asset profile

AB-1002

Gene therapy / editing

Weaksignal

Evidence outlook · lead readout

NCT04179643 · Congestive Heart Failure, Heart Failure, Heart Disease, Ischemic, Cardiovascular Diseases, Heart Failure, Systolic, Heart Failure,Congestive, Heart Arrhythmia, Heart Failure, Diastolic, Heart; Complications

The reported results come from study designs that frequently fail to replicate under controlled conditions — see the rationale below.

NCT04179643: There was no control group, randomization, or blinding: all 11 participants received the active gene therapy, so their outcomes cannot be compared against a placebo or standard-of-care group, and no results have been posted yet.

How the evidence outlook works ↗

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
October 2026 (1)
Phase 2Heart FailureActive not recruiting
Est. primary completion 2026-10-31 · NCT05598333 · CT.gov ↗
What to watch

Research analysis

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See the full readout calendar ↗

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