Head-to-head evidence

Teneligliptin vs Yogliptin

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Type 2 Diabetes

Shared mechanism: DPP-4 · full Type 2 Diabetes pipeline

Teneligliptin · Tenelia

Developed by Mitsubishi Tanabe Pharma

Phase 3 in Type 2 Diabetessmall molecule
Partial signal

NCT00974090 · Phase 3 · completed

The trial was properly randomized and double-blinded with a placebo control and a real hard clinical endpoint (HbA1c change), and enrollment (~96-98 per arm) was reasonable for a 12-week phase 3 add-on study. However, the posted results report only least-squares mean changes with standard errors and no explicit statistical significance test for the primary comparison, so while the numeric difference favors teneligliptin, whether it formally met its pre-specified endpoint cannot be confirmed from this record alone.

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Yogliptin

Developed by Chengdu Easton Biopharmaceuticals

Phase 3 in Type 2 Diabetessmall molecule
Partial signal

NCT05318326 · Phase 3 · status unknown

The trial randomly assigns patients to Yogliptin or a matching placebo and blinds patients, care providers, investigators and outcome assessors alike, using HbA1c change, the standard regulator-accepted measure for diabetes drugs, as its main result. Results have not been posted yet, so whether Yogliptin lowered blood sugar significantly more than placebo is not yet known.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Teneligliptin's landscape · Yogliptin's landscape