Head-to-head evidence

SP2086 vs Yogliptin

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Type 2 Diabetes

Shared mechanism: DPP-4 · full Type 2 Diabetes pipeline

SP2086

Developed by Jiangsu Hengrui Pharmaceuticals

Phase 3 in Type 2 Diabetessmall molecule
Partial signal

NCT01970033 · Phase 3 · status unknown

This is a large, randomized, quadruple-blind, placebo-controlled trial using the standard glycemic control measure for diabetes as its primary endpoint, but no results have been posted yet, so whether the drug lowered HbA1c more than placebo is unknown. (Independently confirmed by a second model, in-session-confirm:claude-opus-20260822.)

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Yogliptin

Developed by Chengdu Easton Biopharmaceuticals

Phase 3 in Type 2 Diabetessmall molecule
Partial signal

NCT05318326 · Phase 3 · status unknown

The trial randomly assigns patients to Yogliptin or a matching placebo and blinds patients, care providers, investigators and outcome assessors alike, using HbA1c change, the standard regulator-accepted measure for diabetes drugs, as its main result. Results have not been posted yet, so whether Yogliptin lowered blood sugar significantly more than placebo is not yet known.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: SP2086's landscape · Yogliptin's landscape