Head-to-head evidence

HS-20137 vs SHR-1139

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Psoriasis

Shared mechanism: IL-23 p19 · full Psoriasis pipeline

HS-20137

Developed by Hansoh Pharmaceutical Group

Phase 3 in Psoriasismonoclonal antibody
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

Next expected readout: March 2027 · NCT06844799 (registry estimate)

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SHR-1139

Developed by Jiangsu Hengrui Pharmaceuticals

Phase 2 in Psoriasismonoclonal antibody (dual IL-23p19/IL-36R)
Partial signal

NCT07051538 · Phase 1 · completed

This early-phase study randomized 64 participants to SHR-1139 or placebo under full blinding, but it was designed to check safety and tolerability, not to test whether the drug improves psoriasis, and no results have been posted, so no conclusion about benefit can yet be drawn from it.

Next expected readout: December 2026 · NCT07719530 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: HS-20137's landscape · SHR-1139's landscape