Head-to-head evidence

HM15275 vs NNC0662-0419

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1/GIP/glucagon receptor (triple) · full Obesity pipeline

HM15275

Developed by Hanmi Pharmaceutical

Phase 2 in Obesitypeptide
Partial signal

NCT06481098 · Phase 1 · completed

The trial randomized participants against a matched placebo with full blinding, but its primary measures were safety and tolerability rather than a body-weight or metabolic efficacy outcome. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

Next expected readout: January 2027 · NCT07205900 (registry estimate)

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NNC0662-0419

Developed by Novo Nordisk

Phase 2 in Obesitypeptide
Partial signal

NCT06737536 · Phase 1 · completed

Participants were randomly assigned to drug or placebo under double-blind conditions across ascending-dose cohorts, a sound early-safety design, but the primary measure was the number of adverse events rather than a weight or clinical outcome, and results have not yet been reported.

Next expected readout: December 2026 · NCT07184632 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: HM15275's landscape · NNC0662-0419's landscape