Head-to-head evidence

HiCM-188 (allogeneic iPSC-cardiomyocytes) vs STM01

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Heart Failure

Shared mechanism: Cardiac cell therapy · full Heart Failure pipeline

HiCM-188 (allogeneic iPSC-cardiomyocytes)

Developed by HELP Therapeutics

Phase 3 in Heart FailureCell therapy (iPSC-derived)
Partial signal

NCT03763136 · Phase 1/2 · completed

The trial randomized 20 participants to hPSC-CM therapy or a sham comparator consisting of coronary artery bypass surgery alone, with outcome assessors masked to treatment assignment. Its primary endpoints were clinical safety outcomes, but results are not posted and the small sample limits the strength of the evidence.

Next expected readout: November 2026 · NCT06340048 (registry estimate)

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STM01

Developed by Secretome Therapeutics

Phase 1 in Heart Failurecell therapy
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: HiCM-188 (allogeneic iPSC-cardiomyocytes)'s landscape · STM01's landscape