Head-to-head evidence

GZR18 vs ZT002

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1 receptor · full Obesity pipeline

GZR18

Developed by Gan & Lee Pharmaceuticals

Phase 3 in Obesitypeptide
Partial signal

NCT06737042 · Phase 2 · completed

The study randomized 326 participants and used quadruple masking with placebo and tirzepatide comparator arms; its primary endpoint was the clinical outcome of percentage change in body weight. Because the primary comparison has not yet been reported, it cannot establish whether GZR18 met its efficacy objective.

Next expected readout: June 2027 · NCT07150975 (registry estimate)

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ZT002

Developed by Beijing QL Biopharmaceutical

Phase 3 in Obesitypeptide
Reliable signal

NCT07020884 · Phase 2 · completed

This randomized, double-blind, placebo-controlled Phase 2 trial (n=303) in adults with overweight or obesity found that ZT002 produced significantly greater weight loss than placebo at 24 weeks across all doses tested, up to 14.4% versus 2.4% with placebo (p<0.0001).

Caveat: this result is taken from a company announcement or a news report of one, not from the trial registry or a peer-reviewed publication. Treat the figures as the sponsor's own statement, not as independently verified evidence.

Next expected readout: December 2026 · NCT07443059 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: GZR18's landscape · ZT002's landscape