Head-to-head evidence

exendin-4 Fc fusion (JY09) vs XW014

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Type 2 Diabetes

Shared mechanism: GLP-1 receptor · full Type 2 Diabetes pipeline

exendin-4 Fc fusion (JY09)

Developed by Beijing Dongfang Biotech

Phase 3 in Type 2 Diabetesprotein
Weak signal

NCT06247748 · Phase 1 · completed

Every participant received the same open-label treatment with no control group, and the study measured drug-interaction and pharmacokinetic markers rather than a clinical benefit. No results have been posted.

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XW014

Developed by Sciwind Biosciences

Phase 1 in Type 2 Diabetessmall molecule
Partial signal

NCT05579314 · Phase 1 · completed

This is a randomized, blinded, placebo-controlled trial, but its primary endpoints are adverse events and routine safety measurements rather than a diabetes outcome such as blood sugar control, and no results have been posted yet.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: exendin-4 Fc fusion (JY09)'s landscape · XW014's landscape