Head-to-head evidence

Evogliptin vs HRX0701

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Type 2 Diabetes

Shared mechanism: DPP-4 · full Type 2 Diabetes pipeline

Evogliptin · Suganon

Developed by Dong-A ST

Phase 3 in Type 2 Diabetessmall molecule
Reliable signal

NCT02949193 · Phase 3 · completed

This was a randomized, quadruple-blind, active-controlled trial (n=222) comparing evogliptin against sitagliptin, both added to metformin. The prespecified non-inferiority comparison for the primary endpoint, HbA1c change at 24 weeks, was met: the between-group difference and its confidence interval stayed within the non-inferiority range.

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HRX0701

Developed by Jiangsu Hengrui Pharmaceuticals

Phase 1 in Type 2 Diabetessmall molecule
Partial signal

NCT05415644 · Phase 1 · completed

This is a randomized, blinded, crossover comparison against the reference formulation, which is a sound design for its purpose, but it measures only drug levels in the blood rather than a diabetes outcome, and no results have been posted yet.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Evogliptin's landscape · HRX0701's landscape