Head-to-head evidence

DA-302168S vs GZR18

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Obesity

Shared mechanism: GLP-1 receptor · full Obesity pipeline

DA-302168S

Developed by Chendu DIAO Pharmaceutical Group

Phase 3 in Obesitysmall molecule
Partial signal

NCT06953063 · Phase 2 · completed

The trial was randomized, quadruple-blind, placebo-controlled, and enrolled 250 participants, with percentage change in body weight as a clinical primary endpoint. However, results are not posted, so it is not possible to determine whether the primary comparison was met; the available evidence therefore supports a moderate grade rather than a strong one.

Next expected readout: July 2027 · NCT07629544 (registry estimate)

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GZR18

Developed by Gan & Lee Pharmaceuticals

Phase 3 in Obesitypeptide
Partial signal

NCT06737042 · Phase 2 · completed

The study randomized 326 participants and used quadruple masking with placebo and tirzepatide comparator arms; its primary endpoint was the clinical outcome of percentage change in body weight. Because the primary comparison has not yet been reported, it cannot establish whether GZR18 met its efficacy objective.

Next expected readout: June 2027 · NCT07150975 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: DA-302168S's landscape · GZR18's landscape