Head-to-head evidence

CT-P17 vs infliximab

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Rheumatoid Arthritis

Shared mechanism: TNF-alpha · full Rheumatoid Arthritis pipeline

CT-P17

Developed by Celltrion

Phase 3 in Rheumatoid Arthritismonoclonal antibody
Partial signal

NCT03789292 · Phase 3 · completed

The trial was a large randomized, quadruple-blind comparison of CT-P17 and Humira, with 324 participants per initial treatment group. Its primary clinical endpoint, ACR20 response at Week 24, had identical reported counts in both groups, but the registry does not state whether the prespecified statistical comparison met its criterion, so the result is unclear.

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infliximab · Remicade

Marketed by Johnson & Johnson and partners

Approved in Rheumatoid Arthritismonoclonal antibody (chimeric IgG1)
Reliable signal

NCT00269867 · Phase 3 · completed

This randomised, double-blind, placebo-controlled trial in 428 patients with rheumatoid arthritis (ATTRACT) reported ACR20 responses of 50-58% across the infliximab plus methotrexate regimens against 20% on placebo plus methotrexate at week 30 (P<0.001 for each regimen), on a validated measure of disease activity.

Next expected readout: March 2028 · NCT03414502 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: CT-P17's landscape · infliximab's landscape