Head-to-head evidence

Aripiprazole (Abilify) vs Brexpiprazole long-acting injection (Kelun)

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Schizophrenia

Shared mechanism: Dopamine D2/D3 and serotonin 5-HT1A receptor · full Schizophrenia pipeline

Aripiprazole (Abilify)

Marketed by Otsuka Holdings and partners

Approved in Schizophreniasmall molecule
Partial signal

NCT00712686 · Phase 3 · completed

The study was a large randomized, double-blind, active-controlled trial comparing aripiprazole with olanzapine, with 690 participants. However, the registry provides no results for either primary endpoint, so it is not possible to determine whether the primary comparisons were favorable or statistically significant.

Next expected readout: September 2027 · NCT07547384 (registry estimate)

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Brexpiprazole long-acting injection (Kelun)

Developed by Sichuan Kelun Pharmaceutical Co., Ltd.

Phase 1 in Schizophreniasmall molecule
not yet graded

No graded featured trial for this indication yet; the grade above reflects that absence, not a judgment.

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Aripiprazole (Abilify)'s landscape · Brexpiprazole long-acting injection (Kelun)'s landscape