Head-to-head evidence

Anplag tab vs Sarpogrelate

Same mechanism, same race: design-graded trial evidence for both assets, with the grading rationale shown. Grades describe the quality of the evidence, never the merits of either security.

Atherosclerotic Cardiovascular Disease

Shared mechanism: Serotonin 5-HT2A receptor (antagonist / inverse agonist) · full Atherosclerotic Cardiovascular Disease pipeline

Anplag tab

Developed by Yuhan Corporation

Phase 3 in Atherosclerotic Cardiovascular Diseasesmall molecule
Partial signal

NCT02393612 · Phase 3 · completed

The study randomly assigned 151 participants to an active comparator and used triple masking of participants, investigators, and outcome assessors. Registry results were not posted at the time of grading; the key result shown was recovered from the cited external source.

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Sarpogrelate · Anplag

Developed by Yuhan Corporation

Phase 3 in Atherosclerotic Cardiovascular Diseasesmall molecule
Reliable signal

NCT02393612 · Phase 3 · completed

This randomized, triple-blind, active-controlled trial in 151 patients with peripheral arterial disease compared a once-daily sarpogrelate formulation with the established three-times-daily formulation over 12 weeks and found the once-daily version met its prespecified non-inferiority margin for reducing leg pain, with no meaningful differences on secondary measures.

Next expected readout: June 2028 · NCT06424548 (registry estimate)

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The full competitive landscape for each asset (every same-race competitor with aligned evidence, sortable) is on the asset pages: Anplag tab's landscape · Sarpogrelate's landscape