Mechanism
TROP2 and EGFR (dual)
Assets acting on this target.
- Class
- TROP2/EGFR bispecific antibody-drug conjugate (MMAE payload)
- Pathway
- Bispecific antibody simultaneously binds TROP2 and EGFR on tumor cells, delivering the microtubule-disrupting payload MMAE via a protease-cleavable linker
Research
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