Mechanism

Sphingosine-1-phosphate receptors 1 and 5 (S1P1, S1P5)

Assets acting on this target.

Class
Small molecule S1P receptor modulator
Pathway
Selective S1P1 receptor internalization sequesters lymphocytes in lymph nodes, reducing circulating lymphocyte migration into the CNS and gut (confirmed as ozanimod/Zeposia via CT.gov intervention cross-references)
Research

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