Mechanism
NKG2A/CD94 heterodimer (blocks HLA-E interaction)
Assets acting on this target.
- Class
- Anti-NKG2A fully human IgG1 monoclonal antibody (Servier)
- Pathway
- Restores NK-cell and CD8+ T-cell cytotoxic activity by preventing NKG2A/HLA-E inhibitory signaling
Research
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