Mechanism

Mutant NPM1 (dNPM1 peptides)

Assets acting on this target.

Class
Autologous TCR-T cell therapy (lentiviral-engineered)
Pathway
T-cell receptor recognition of dNPM1 neoantigen peptides presented on leukemic cells
Research

Explore this mechanism at different depths

Research adds deeper and simplified explanation variants while preserving the same scientific register and source caveats.

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