Mechanism
Ly6E
Assets acting on this target.
- Class
- Ly6E-directed antibody-drug conjugate (exatecan/topoisomerase-I-inhibitor payload)
- Pathway
- antibody binds Ly6E, overexpressed on multiple solid tumor types (NSCLC, TNBC, ovarian, head and neck, pancreatic, gastric), delivering an exatecan payload upon internalization
Research
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