Mechanism
Gut microbiome-immune axis
Assets acting on this target.
- Class
- Live biotherapeutic product (Akkermansia muciniphila) used as an immune-checkpoint-inhibitor sensitizer
- Pathway
- Colonization stimulates dendritic cell activation and CD4+/CD8+ T-cell trafficking/activation, restoring or enhancing response to anti-PD-(L)1 immunotherapy
- Notes
- original target text: Gut microbiome-immune axis (no single molecular receptor; a live bacterial biotherapeutic)
Research
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