Mechanism
Glypican-3 (GPC3)
Assets acting on this target.
- Class
- GPC3-directed antibody-drug conjugate (ZD06519, camptothecin-derived topoisomerase-1 inhibitor payload, DAR4, cleavable linker)
- Pathway
- Antibody-mediated internalization delivering a bystander-active topoisomerase I inhibitor
Research
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