Mechanism
Complement C3 / C3b
Assets acting on this target.
- Class
- PEGylated cyclic peptide complement inhibitor (pegcetacoplan; brand SYFOVRE)
- Pathway
- Binds complement protein C3 and its activation fragment C3b, regulating C3 cleavage and blocking downstream effector generation across the classical, lectin, and alternative complement activation pathways, which converge at C3
Research
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