Mechanism
Complement C3 / C3b
Assets acting on this target.
- Class
- PEGylated cyclic peptide complement inhibitor (pegcetacoplan; brand SYFOVRE)
- Pathway
- Binds complement protein C3 and its activation fragment C3b, regulating C3 cleavage and blocking downstream effector generation across the classical, lectin, and alternative complement activation pathways, which converge at C3