Mechanism
CB2 receptor and PPARγ (dual agonist)
Assets acting on this target.
- Class
- semi-synthetic cannabinoquinone (cannabidiol-quinone derivative); dev codes VCE-004.8 / EHP-101
- Pathway
- Dual CB2/PPARγ receptor agonism, plus PP2A/B55α activation and prolyl-hydroxylase (PHD) inhibition driving HIF pathway activation; net anti-inflammatory, anti-fibrotic and pro-angiogenic effect being tested in peripheral arterial disease