Mechanism
Bile acids (gastrointestinal lumen)
Assets acting on this target.
- Class
- Soluble dietary fiber (bile-acid-binding, bulk-forming laxative/lipid-lowering agent)
- Pathway
- Binds bile acids in the gut lumen, increasing their fecal excretion; the liver compensates by converting more cholesterol into bile acids, upregulating LDL receptor expression and lowering LDL-C
Research
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