Asset profile

Vosoritide · VOXZOGO

Peptide

Approved / Phase 4Mechanism not established
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Approvedregulatory verdict

Evidence outlook

Approved: Achondroplasia

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

Also in development:Hypochondroplasia · Phase 3

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Competitive landscape

1 competitor in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 1 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Vosoritide (VOXZOGO): this drugApprovedPeptide—
BMN 333Phase 2/3Peptide—
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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(8 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (3)
March 2027 (1)
Phase 2Noonan SyndromeActive not recruiting
Est. primary completion 2027-03 · NCT06668805 · CT.gov ↗
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December 2027 (2)
Phase 2AchondroplasiaActive not recruiting
Est. primary completion 2027-12 · NCT02724228 · CT.gov ↗
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Phase 2AchondroplasiaActive not recruiting
Est. primary completion 2027-12 · NCT04554940 · CT.gov ↗
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2028 (2)
June 2028 (1)
Phase 2HypochondroplasiaRecruiting
Est. primary completion 2028-06-30 · NCT07126262 · CT.gov ↗
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December 2028 (1)
Phase 1/2MPS IVA, MPS VIActive not recruiting
Est. primary completion 2028-12-31 · NCT05845749 · CT.gov ↗
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2031 (1)
June 2031 (1)
Phase 3AchondroplasiaActive not recruiting
Est. primary completion 2031-06 · NCT03424018 · CT.gov ↗
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2038 (1)
May 2038 (1)
Phase 2AchondroplasiaActive not recruiting
Est. primary completion 2038-05 · NCT03989947 · CT.gov ↗
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2044 (1)
October 2044 (1)
Phase 3HypochondroplasiaEnrolling by invitation
Est. primary completion 2044-10 · NCT07073014 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (4)
Phase 2 (10)
Phase 1/2 (1)
Phase 1 (2)
Used as active comparator (1)