Asset profile

TPST-1120

Small molecule

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Phase 3underway

Evidence outlook · registrational

Hepatocellular Carcinoma: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2028-12.

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Competitive landscape

3 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 3 same-indication; 1 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
TPST-1120: this drugPhase 3Small moleculePPARα (peroxisome proliferator-activated receptor alpha)
CabozantinibApprovedSmall moleculeMulti-kinase inhibitor (VEGFR/PDGFR/KIT)
NamodenosonPhase 3—Adenosine A3 receptor
SENTI-301ANot yet studiedCell therapy—
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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
July 2027 (1)
Phase 1/2Advanced Liver CancersActive not recruiting
Est. primary completion 2027-07-30 · NCT04524871 · CT.gov ↗
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2028 (1)
December 2028 (1)
Phase 3Hepatocellular CarcinomaNot yet recruiting
Est. primary completion 2028-12 · NCT06680258 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 1/2 (1)
Phase 1 (1)