Asset profile

Temozolomide

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: adult patients with: Newly diagnosed glioblastoma concomitantly with radiotherapy and... (FDA)

This approval is for an indication outside this terminal's covered markets; the covered program shown here is investigational. Regulatory approval supersedes design-level evidence grading for the approved use.

Source for the program status

How the evidence outlook works ↗

Competitive landscape

No competitors sharing a mechanism or indication in the current universe.

Upcoming events

(172 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (31)
October 2026 (1)
Phase 1Small Cell Lung CancerRecruiting
Est. primary completion 2026-10-30 · NCT06931626 · CT.gov ↗
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November 2026 (5)
Phase 3High-Risk Neuroblastoma, Patient With Insufficient Response ChemoimmunotherapyRecruiting
Est. primary completion 2026-11 · NCT04221035 · CT.gov ↗
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Phase 2Glioblastoma Multiforme, Glioblastoma Multiforme, Adult, Supratentorial Glioblastoma, Supratentorial GliosarcomaRecruiting
Est. primary completion 2026-11-01 · NCT05052957 · CT.gov ↗
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Phase 2GlioblastomaActive not recruiting
Est. primary completion 2026-11-19 · NCT04574856 · CT.gov ↗
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Phase 1Glioblastoma MultiformeRecruiting
Est. primary completion 2026-11-30 · NCT05769660 · CT.gov ↗
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Phase 2GlioblastomaActive not recruiting
Est. primary completion 2026-11-30 · NCT05781321 · CT.gov ↗
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December 2026 (25)
Phase 1High Grade Glioma, GlioblastomaRecruiting
Est. primary completion 2026-12 · NCT06072586 · CT.gov ↗
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Phase 1Solid Tumors, Neuroblastoma, Rhabdomyosarcoma, Ewing Sarcoma, Hepatoblastoma, MedulloblastomaActive not recruiting
Est. primary completion 2026-12 · NCT04337177 · CT.gov ↗
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Phase 1Neuroblastoma, Refractory Neuroblastoma, Relapsed Neuroblastoma, Relapsed Osteosarcoma, Refractory OsteosarcomaRecruiting
Est. primary completion 2026-12 · NCT05400603 · CT.gov ↗
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Phase 1Malignant Glioma of BrainActive not recruiting
Est. primary completion 2026-12 · NCT03011671 · CT.gov ↗
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Phase 1/2Glioblastoma, Melanoma Stage IV, Breast Cancer, Prostate Cancer, Glioblastoma Multiforme, GBM, Brain Cancer, Metastatic Breast Cancer …Active not recruiting
Est. primary completion 2026-12 · NCT04478279 · CT.gov ↗
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Phase 1/2Glioma, MalignantNot yet recruiting
Est. primary completion 2026-12 · NCT06258018 · CT.gov ↗
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Phase 1/2GlioblastomaActive not recruiting
Est. primary completion 2026-12 · NCT04019262 · CT.gov ↗
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Phase 1/2Relapsed Neuroblastoma, Refractory NeuroblastomaActive not recruiting
Est. primary completion 2026-12 · NCT04211675 · CT.gov ↗
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Phase 2Neuroendocrine Carcinomas (NEC)Not yet recruiting
Est. primary completion 2026-12 · NCT07156019 · CT.gov ↗
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Phase 2Gastrointestinal Stromal TumorsRecruiting
Est. primary completion 2026-12-01 · NCT05661643 · CT.gov ↗
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Phase 3Neuroblastoma (NB), GanglioneuroblastomaRecruiting
Est. primary completion 2026-12-15 · NCT07375563 · CT.gov ↗
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Phase 1Lymphoma, Primary Central Nervous System LymphomaRecruiting
Est. primary completion 2026-12-30 · NCT06475235 · CT.gov ↗
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Phase 1/2GlioblastomaRecruiting
Est. primary completion 2026-12-30 · NCT03643549 · CT.gov ↗
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Phase 1Refractory Solid TumorsRecruiting
Est. primary completion 2026-12-31 · NCT06006273 · CT.gov ↗
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Phase 1/2GliomaRecruiting
Est. primary completion 2026-12-31 · NCT06703255 · CT.gov ↗
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Phase 1/2MelanomaRecruiting
Est. primary completion 2026-12-31 · NCT05983237 · CT.gov ↗
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Phase 1/2Recurrent Solid Tumor, Recurrent Ewing Sarcoma, Recurrent Hepatoblastoma, Recurrent Malignant Germ Cell Tumor …Recruiting
Est. primary completion 2026-12-31 · NCT04901702 · CT.gov ↗
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Phase 1/2GlioblastomaActive not recruiting
Est. primary completion 2026-12-31 · NCT03491683 · CT.gov ↗
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Phase 2Anaplastic Astrocytoma, IDH-Wildtype, Anaplastic Oligoastrocytoma, Anaplastic Oligodendroglioma, Diffuse Astrocytoma, IDH-Wildtype …Recruiting
Est. primary completion 2026-12-31 · NCT04623931 · CT.gov ↗
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Phase 2NeuroblastomaRecruiting
Est. primary completion 2026-12-31 · NCT06013618 · CT.gov ↗
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Phase 2Solid Tumor, Precision MedicineRecruiting
Est. primary completion 2026-12-31 · NCT06739395 · CT.gov ↗
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Phase 2Pan-tumorRecruiting
Est. primary completion 2026-12-31 · NCT04566380 · CT.gov ↗
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Phase 2GlioblastomaActive not recruiting
Est. primary completion 2026-12-31 · NCT04959500 · CT.gov ↗
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Phase 3Brain and Central Nervous System Tumors, NeurotoxicityActive not recruiting
Est. primary completion 2026-12-31 · NCT00978458 · CT.gov ↗
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Phase 3GliomaRecruiting
Est. primary completion 2026-12-31 · NCT06330337 · CT.gov ↗
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2027 (52)
January 2027 (5)
Phase 1/2Solid Tumor, RhabdomyosarcomaRecruiting
Est. primary completion 2027-01 · NCT04796012 · CT.gov ↗
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Phase 2GlioblastomaActive not recruiting
Est. primary completion 2027-01 · NCT04485949 · CT.gov ↗
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Phase 2GliomaRecruiting
Est. primary completion 2027-01 · NCT05188508 · CT.gov ↗
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Phase 1/2Advanced Malignant Solid Neoplasm, Extensive Stage Lung Small Cell Carcinoma, Stage III Lung Cancer AJCC v8 …Active not recruiting
Est. primary completion 2027-01-03 · NCT03830918 · CT.gov ↗
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Phase 2MGMT-Methylated Glioblastoma, Glioblastoma (GBM), Newly Diagnosed Glioblastoma MultiformeRecruiting
Est. primary completion 2027-01-31 · NCT06649851 · CT.gov ↗
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February 2027 (5)
Phase 1GlioblastomaActive not recruiting
Est. primary completion 2027-02 · NCT02287428 · CT.gov ↗
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Phase 2GliomaActive not recruiting
Est. primary completion 2027-02 · NCT06413706 · CT.gov ↗
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Early phase / not applicablePrimary Central Nervous System LymphomaRecruiting
Est. primary completion 2027-02-13 · NCT06832267 · CT.gov ↗
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Phase 1GlioblastomaActive not recruiting
Est. primary completion 2027-02-15 · NCT04047706 · CT.gov ↗
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Phase 2Glioblastoma Multiforme (GBM)Active not recruiting
Est. primary completion 2027-02-28 · NCT04587830 · CT.gov ↗
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March 2027 (5)
Phase 1/2Pilomyxoid Astrocytoma, Pilocytic Astrocytoma, Glioma, Astrocytic, Optic Nerve Glioma, Pleomorphic Xanthoastrocytoma …Active not recruiting
Est. primary completion 2027-03 · NCT01837862 · CT.gov ↗
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Phase 1/2Advanced Malignant Solid Neoplasm, Advanced Microsatellite Stable Colorectal Carcinoma, Hematopoietic and Lymphatic System Neoplasm …Recruiting
Est. primary completion 2027-03-01 · NCT05691491 · CT.gov ↗
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Phase 1Malignant GliomaRecruiting
Est. primary completion 2027-03-15 · NCT05030298 · CT.gov ↗
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Phase 2Metastatic Malignant Neoplasm in the Liver, Pancreatic Neuroendocrine Tumor, Stage I Pancreatic Neuroendocrine Tumor AJCC v8 …Recruiting
Est. primary completion 2027-03-31 · NCT05040360 · CT.gov ↗
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Phase 2GlioblastomaActive not recruiting
Est. primary completion 2027-03-31 · NCT03688178 · CT.gov ↗
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April 2027 (4)
Phase 2Ewing SarcomaRecruiting
Est. primary completion 2027-04 · NCT06827717 · CT.gov ↗
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Phase 2Glioblastoma (GBM)Recruiting
Est. primary completion 2027-04-01 · NCT07193654 · CT.gov ↗
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Phase 3Glioblastoma, Glioblastoma Multiforme, Glioma, Malignant, GBM, Brain Cancer, Glioblastoma, IDH-wildtype, Glioblastoma Multiforme, AdultRecruiting
Est. primary completion 2027-04-01 · NCT05271240 · CT.gov ↗
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Phase 1/2Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma …Recruiting
Est. primary completion 2027-04-15 · NCT05588453 · CT.gov ↗
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May 2027 (5)
Phase 2Newly Diagnosed Ewing SarcomaActive not recruiting
Est. primary completion 2027-05 · NCT01864109 · CT.gov ↗
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Phase 2Neoplasms, Child, AdolescentRecruiting
Est. primary completion 2027-05 · NCT05999994 · CT.gov ↗
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Early phase / not applicableIDH-Wildtype Glioblastoma, Glioblastoma (GBM)Recruiting
Est. primary completion 2027-05 · NCT06850766 · CT.gov ↗
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Phase 2Ewing's SarcomaNot yet recruiting
Est. primary completion 2027-05-01 · NCT07092306 · CT.gov ↗
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Phase 1/2Glioblastoma, Diffuse GliomaActive not recruiting
Est. primary completion 2027-05-30 · NCT04910022 · CT.gov ↗
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June 2027 (4)
Phase 1Neuroblastoma (NB)Active not recruiting
Est. primary completion 2027-06 · NCT03189706 · CT.gov ↗
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Phase 3GlioblastomaActive not recruiting
Est. primary completion 2027-06 · NCT03663725 · CT.gov ↗
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Phase 1/2Recurrent Glioblastoma, IDH-Wildtype, Recurrent MGMT-Methylated GlioblastomaRecruiting
Est. primary completion 2027-06-30 · NCT05432804 · CT.gov ↗
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Phase 2Glioblastoma MultiformeActive not recruiting
Est. primary completion 2027-06-30 · NCT03862430 · CT.gov ↗
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July 2027 (3)
Phase 1Recurrent High Grade Glioma, Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, Glioblastoma, GliosarcomaRecruiting
Est. primary completion 2027-07 · NCT05698524 · CT.gov ↗
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Phase 1/2Glioblastoma Multiforme of BrainActive not recruiting
Est. primary completion 2027-07 · NCT02649582 · CT.gov ↗
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Phase 1Neuroblastoma, Neuroblastoma Recurrent, Relapsed Neuroblastoma, Refractory NeuroblastomaRecruiting
Est. primary completion 2027-07-01 · NCT07027748 · CT.gov ↗
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August 2027 (2)
Phase 1Sarcoma, Desmoplastic Small Round Cell Tumor (DSRCT)Active not recruiting
Est. primary completion 2027-08 · NCT01189643 · CT.gov ↗
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Phase 1Newly Diagnosed and Recurrent GlioblastomaActive not recruiting
Est. primary completion 2027-08-10 · NCT05739942 · CT.gov ↗
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September 2027 (4)
Phase 1Brain TumorRecruiting
Est. primary completion 2027-09-01 · NCT03122197 · CT.gov ↗
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Early phase / not applicableLymphoma CnsRecruiting
Est. primary completion 2027-09-02 · NCT07191431 · CT.gov ↗
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Phase 1/2Neuroendocrine TumorsRecruiting
Est. primary completion 2027-09-15 · NCT06038461 · CT.gov ↗
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Phase 2Glioblastoma MultiformeActive not recruiting
Est. primary completion 2027-09-16 · NCT04116411 · CT.gov ↗
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October 2027 (5)
Phase 1Glioma, Diffuse Astrocytoma, IDH-Wildtype (Grade 2-4), Glioblastoma, IDH-wildtype, Diffuse Midline Glioma, H3 K27-Altered …Recruiting
Est. primary completion 2027-10 · NCT07223034 · CT.gov ↗
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Phase 2GlioblastomaRecruiting
Est. primary completion 2027-10 · NCT07476794 · CT.gov ↗
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Phase 2Ovary Cancer, Fallopian Tube Cancer, Primary Peritoneal Cavity CancerRecruiting
Est. primary completion 2027-10 · NCT06617923 · CT.gov ↗
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Early phase / not applicableGlioblastoma, IDH Wild-type and STAT3-positive GlioblastomaRecruiting
Est. primary completion 2027-10 · NCT06964815 · CT.gov ↗
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Phase 1/2Relapsed/Refractory GliomaRecruiting
Est. primary completion 2027-10-10 · NCT07599371 · CT.gov ↗
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November 2027 (2)
Phase 1/2IDH1-mutant Glioma, IDH2-mutant GliomaActive not recruiting
Est. primary completion 2027-11 · NCT06478212 · CT.gov ↗
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Phase 2GlioblastomaRecruiting
Est. primary completion 2027-11-09 · NCT06297512 · CT.gov ↗
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December 2027 (8)
Phase 2Glioblastoma, GBMRecruiting
Est. primary completion 2027-12 · NCT07225621 · CT.gov ↗
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Phase 2Relapsed or Refractory Pediatric Malignant Solid Tumors (Including Neuroblastoma, Rhabdomyosarcoma, Ewing Sarcoma, Osteosarcoma)Not yet recruiting
Est. primary completion 2027-12-01 · NCT07444918 · CT.gov ↗
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Phase 2GlioblastomaRecruiting
Est. primary completion 2027-12-01 · NCT07670026 · CT.gov ↗
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Phase 2Extensive Stage Lung Small Cell Carcinoma, Metastatic Lung Small Cell Carcinoma, Recurrent Lung Small Cell Carcinoma …Recruiting
Est. primary completion 2027-12-30 · NCT04919382 · CT.gov ↗
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Phase 1Glioblastoma, GliosarcomaActive not recruiting
Est. primary completion 2027-12-31 · NCT04555577 · CT.gov ↗
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Phase 2Glioblastoma MultiformeNot yet recruiting
Est. primary completion 2027-12-31 · NCT06218524 · CT.gov ↗
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Phase 2Head and Neck Mucosal MelanomasNot yet recruiting
Est. primary completion 2027-12-31 · NCT07353073 · CT.gov ↗
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Phase 2Glioblastoma MultiformeActive not recruiting
Est. primary completion 2027-12-31 · NCT02344355 · CT.gov ↗
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2028 (38)
January 2028 (6)
Phase 1Glioblastoma MultiformeRecruiting
Est. primary completion 2028-01 · NCT05083754 · CT.gov ↗
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Phase 2Recurrent GlioblastomaRecruiting
Est. primary completion 2028-01 · NCT07297212 · CT.gov ↗
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Phase 2Glioma, MalignantNot yet recruiting
Est. primary completion 2028-01-03 · NCT07707973 · CT.gov ↗
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Phase 2LymphomaRecruiting
Est. primary completion 2028-01-09 · NCT07015242 · CT.gov ↗
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Phase 1/2High Grade Glioma, MGMT-Unmethylated Glioblastoma, MGMT-Methylated GlioblastomaRecruiting
Est. primary completion 2028-01-31 · NCT06504381 · CT.gov ↗
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Phase 2Soft Tissue Sarcoma (Excluding GIST)Not yet recruiting
Est. primary completion 2028-01-31 · NCT07457775 · CT.gov ↗
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February 2028 (3)
Phase 2Neuroblastoma RecurrentRecruiting
Est. primary completion 2028-02-01 · NCT07085338 · CT.gov ↗
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Phase 2GlioblastomaRecruiting
Est. primary completion 2028-02-01 · NCT02977780 · CT.gov ↗
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Phase 1/2Advanced Solid MalignanciesRecruiting
Est. primary completion 2028-02-07 · NCT05417594 · CT.gov ↗
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March 2028 (3)
Phase 2Advanced Adrenal Gland Pheochromocytoma, Advanced Paraganglioma, Metastatic Adrenal Gland Pheochromocytoma, Metastatic Paraganglioma …Active not recruiting
Est. primary completion 2028-03-01 · NCT04394858 · CT.gov ↗
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Phase 1Ependymoma, Medulloblastoma, Glioblastoma, Primary Brain TumorRecruiting
Est. primary completion 2028-03-30 · NCT05106296 · CT.gov ↗
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Phase 2Metastatic Pancreatic Neuroendocrine Tumor, Unresectable Pancreatic Neuroendocrine CarcinomaActive not recruiting
Est. primary completion 2028-03-31 · NCT05247905 · CT.gov ↗
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April 2028 (2)
Phase 1Glioblastoma, GliosarcomaRecruiting
Est. primary completion 2028-04 · NCT06934889 · CT.gov ↗
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Phase 2Breast Cancer Triple NegativeNot yet recruiting
Est. primary completion 2028-04-01 · NCT05128734 · CT.gov ↗
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May 2028 (3)
Phase 1/2Wilms TumorRecruiting
Est. primary completion 2028-05 · NCT05384821 · CT.gov ↗
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Phase 2Glioblastoma, IDH-wildtypeRecruiting
Est. primary completion 2028-05 · NCT04945148 · CT.gov ↗
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Phase 1/2Malignant Neoplasm, Malignant Neoplasm of BrainRecruiting
Est. primary completion 2028-05-30 · NCT06012695 · CT.gov ↗
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June 2028 (4)
Phase 1High-grade GliomaNot yet recruiting
Est. primary completion 2028-06 · NCT07457307 · CT.gov ↗
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Phase 1/2Glioblastoma Multiforme (GBM), Glioblastoma, Glioma of Brain, Glioblastoma, Adult, Brain Tumor, Brain Tumor, Primary, Brain Tumor Adult …Recruiting
Est. primary completion 2028-06 · NCT03213002 · CT.gov ↗
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Phase 1NeuroblastomaRecruiting
Est. primary completion 2028-06-01 · NCT06995872 · CT.gov ↗
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Phase 2High Grade Glioma, Diffuse Intrinsic Pontine Glioma, Recurrent MedulloblastomaRecruiting
Est. primary completion 2028-06-15 · NCT05096481 · CT.gov ↗
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July 2028 (3)
Phase 1/2Cytokine-Induced Killer Cells, Milignant GliomasNot yet recruiting
Est. primary completion 2028-07 · NCT02494804 · CT.gov ↗
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Phase 4Cytokine-Induced Killer Cells, Advanced Milignant GliomasNot yet recruiting
Est. primary completion 2028-07 · NCT02496988 · CT.gov ↗
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Phase 2Neuroendocrine Tumor Grade 2, Neuroendocrine TumorsRecruiting
Est. primary completion 2028-07-01 · NCT04339036 · CT.gov ↗
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August 2028 (2)
Phase 1/2Advanced Cancer, Metastatic Solid TumorRecruiting
Est. primary completion 2028-08 · NCT05004116 · CT.gov ↗
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Phase 2Solid TumorsRecruiting
Est. primary completion 2028-08-15 · NCT07492680 · CT.gov ↗
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September 2028 (3)
Phase 1/2Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype, Astrocytoma, Grade IIIRecruiting
Est. primary completion 2028-09 · NCT05765812 · CT.gov ↗
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Phase 2High Grade Gliomas, Glioblastoma, Astrocytoma, OligodendrogliomaNot yet recruiting
Est. primary completion 2028-09 · NCT07439172 · CT.gov ↗
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Phase 1GliomaRecruiting
Est. primary completion 2028-09-01 · NCT07025226 · CT.gov ↗
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November 2028 (2)
Phase 2Glioblastoma (GBM), Newly Diagnosed Glioblastoma, GBM, Glioblastoma Multiforme (GBM), Glioma, Central Nervous System Diseases, Brain CancerRecruiting
Est. primary completion 2028-11 · NCT07326566 · CT.gov ↗
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Phase 1/2Sarcoma, Sarcoma, Ewing, Desmoplastic Small Round Cell Tumor, Refractory Sarcoma, Osteosarcoma, RhabdomyosarcomaRecruiting
Est. primary completion 2028-11-01 · NCT06709495 · CT.gov ↗
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December 2028 (7)
Phase 1Ewing Sarcoma, Colorectal AdenocarcinomaRecruiting
Est. primary completion 2028-12 · NCT03715933 · CT.gov ↗
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Phase 2Pancreatic CancerActive not recruiting
Est. primary completion 2028-12 · NCT03351296 · CT.gov ↗
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Phase 2NeuroblastomaRecruiting
Est. primary completion 2028-12 · NCT06450041 · CT.gov ↗
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Phase 2GlioblastomaNot yet recruiting
Est. primary completion 2028-12-24 · NCT07365280 · CT.gov ↗
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Phase 2Neuroblastoma (NB), Neuroblastoma in ChildrenRecruiting
Est. primary completion 2028-12-31 · NCT07318831 · CT.gov ↗
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Phase 3GlioblastomaRecruiting
Est. primary completion 2028-12-31 · NCT05439278 · CT.gov ↗
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Early phase / not applicableMetastatic Sarcoma, Recurrent Sarcoma, Resectable SarcomaRecruiting
Est. primary completion 2028-12-31 · NCT04199026 · CT.gov ↗
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2029 (22)
January 2029 (4)
Phase 2Glioblastoma MultiformeNot yet recruiting
Est. primary completion 2029-01 · NCT01777919 · CT.gov ↗
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Phase 2Primary GlioblastomaNot yet recruiting
Est. primary completion 2029-01 · NCT07347210 · CT.gov ↗
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Phase 1Astrocytoma, Glioblastoma, Glioblastoma, IDH-Wildtype, MGMT-Unmethylated Glioblastoma, Recurrent GlioblastomaActive not recruiting
Est. primary completion 2029-01-03 · NCT05236036 · CT.gov ↗
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Phase 1/2Malignant Primary Gliomas, Glioblastoma Multiforme (GBM)Recruiting
Est. primary completion 2029-01-19 · NCT07391215 · CT.gov ↗
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February 2029 (1)
Phase 1GlioblastomaRecruiting
Est. primary completion 2029-02-28 · NCT06831526 · CT.gov ↗
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March 2029 (1)
Phase 2/3Recurrent Glioblastoma, IDH-WildtypeNot yet recruiting
Est. primary completion 2029-03-30 · NCT07349693 · CT.gov ↗
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April 2029 (2)
Phase 3GlioblastomaRecruiting
Est. primary completion 2029-04 · NCT06556563 · CT.gov ↗
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Phase 1High Grade GliomaRecruiting
Est. primary completion 2029-04-30 · NCT06428045 · CT.gov ↗
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July 2029 (2)
Phase 2High-risk Neuroblastoma, Neuroblastoma, Childhood NeuroblastomaRecruiting
Est. primary completion 2029-07-22 · NCT06528496 · CT.gov ↗
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Phase 2Glioma, Glioblastoma (GBM), MGMT-Methylated GlioblastomaNot yet recruiting
Est. primary completion 2029-07-31 · NCT07754734 · CT.gov ↗
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August 2029 (3)
Phase 2GlioblastomaNot yet recruiting
Est. primary completion 2029-08-01 · NCT07758062 · CT.gov ↗
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Phase 2CancerRecruiting
Est. primary completion 2029-08-25 · NCT03899155 · CT.gov ↗
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Phase 2High Grade Glioma, Diffuse Intrinsic Pontine Glioma, Anaplastic Astrocytoma, Glioblastoma, Glioblastoma Multiforme, Diffuse Midline Glioma …Recruiting
Est. primary completion 2029-08-31 · NCT05843253 · CT.gov ↗
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September 2029 (5)
Phase 2Melanoma (Skin Cancer)Not yet recruiting
Est. primary completion 2029-09-01 · NCT07501104 · CT.gov ↗
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Phase 1/2Malignant Neoplasm of BrainRecruiting
Est. primary completion 2029-09-30 · NCT07569042 · CT.gov ↗
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Phase 1/2Glioblastoma Multiforme (GBM), Glioblastoma Multiform (Grade IV Astrocytoma), Diffuse Hemispheric Glioma, H3 G34-Mutant …Recruiting
Est. primary completion 2029-09-30 · NCT06630260 · CT.gov ↗
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Phase 2Mucosal Melanoma, PD-L1 PositiveRecruiting
Est. primary completion 2029-09-30 · NCT07400302 · CT.gov ↗
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Phase 2/3Advanced GlioblastomaNot yet recruiting
Est. primary completion 2029-09-30 · NCT07605364 · CT.gov ↗
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October 2029 (2)
Phase 1/2Glioma, CNS Tumor, Adult, CNS Tumor, ChildhoodRecruiting
Est. primary completion 2029-10 · NCT07243470 · CT.gov ↗
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Phase 3Brain and Central Nervous System TumorsActive not recruiting
Est. primary completion 2029-10-31 · NCT00887146 · CT.gov ↗
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December 2029 (2)
Phase 1/2Relapsed Small Cell Lung Cancer, Recurrent Small Cell Lung CancerRecruiting
Est. primary completion 2029-12-31 · NCT06681220 · CT.gov ↗
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Phase 3Ganglioneuroblastoma, Nodular, NeuroblastomaRecruiting
Est. primary completion 2029-12-31 · NCT06172296 · CT.gov ↗
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2030 (18)
January 2030 (1)
Phase 3Glioblastoma, IDH-Wildtype, MGMT-Unmethylated GlioblastomaRecruiting
Est. primary completion 2030-01-15 · NCT07452458 · CT.gov ↗
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March 2030 (1)
Phase 2Glioblastoma (GBM)Recruiting
Est. primary completion 2030-03 · NCT06805305 · CT.gov ↗
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April 2030 (2)
Phase 1/2Refractory Solid Tumors, Relapsed Solid Tumors, Relapsed Neuroblastoma, Refractory Neuroblastoma, Relapsed Rhabdomyosarcoma …Recruiting
Est. primary completion 2030-04 · NCT06721689 · CT.gov ↗
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Phase 2Medulloblastoma Recurrent, Ependymoma Recurrent, ATRT Recurrent, Rare CNS Tumor RecurrentRecruiting
Est. primary completion 2030-04 · NCT01356290 · CT.gov ↗
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June 2030 (1)
Phase 1/2SCLC, Extensive StageNot yet recruiting
Est. primary completion 2030-06-30 · NCT07141771 · CT.gov ↗
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July 2030 (1)
Phase 1/2Glioblastoma MultiformeNot yet recruiting
Est. primary completion 2030-07-30 · NCT04373785 · CT.gov ↗
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September 2030 (2)
Phase 1/2Glioblastoma (GBM)Not yet recruiting
Est. primary completion 2030-09 · NCT07762716 · CT.gov ↗
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Phase 2Embryonal Tumor With Multilayered Rosettes, Embryonal Tumor With Multilayered Rosettes, NosRecruiting
Est. primary completion 2030-09-30 · NCT06861244 · CT.gov ↗
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October 2030 (2)
Phase 1Metastatic Ewing SarcomaRecruiting
Est. primary completion 2030-10 · NCT07194044 · CT.gov ↗
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Phase 1Progressive Pediatric Brain CancerNot yet recruiting
Est. primary completion 2030-10-08 · NCT07732413 · CT.gov ↗
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November 2030 (3)
Phase 1/2Diffuse Midline Glioma, H3 K27-AlteredNot yet recruiting
Est. primary completion 2030-11 · NCT07562971 · CT.gov ↗
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Phase 2/3Glioblastoma Multiforme of BrainActive not recruiting
Est. primary completion 2030-11 · NCT05685004 · CT.gov ↗
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Phase 1/2Neuroblastoma, Ewing Sarcoma, Osteosarcoma, Rhabdomyosarcoma, LiposarcomaRecruiting
Est. primary completion 2030-11-01 · NCT06541262 · CT.gov ↗
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December 2030 (5)
Phase 1/2Childhood Cancer, Childhood Solid Tumor, Childhood Brain Tumor, Recurrent Cancer, Refractory CancerRecruiting
Est. primary completion 2030-12 · NCT06208657 · CT.gov ↗
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Phase 2Glioblastoma, Brain Cancer, Glioblastoma Multiforme, Glioblastoma Multiforme of Brain, Glioblastoma Multiforme, Adult …Recruiting
Est. primary completion 2030-12 · NCT06991101 · CT.gov ↗
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Phase 3GlioblastomaNot yet recruiting
Est. primary completion 2030-12-01 · NCT06448286 · CT.gov ↗
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Phase 1CNS Embryonal Tumor, CNS, Medulloblastoma, Atypical Teratoid Rhabdoid Tumor, Medulloblastoma, Childhood, Medulloblastoma, Group 3 …Recruiting
Est. primary completion 2030-12-31 · NCT06942039 · CT.gov ↗
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Phase 1/2Relapsed NeuroblastomaRecruiting
Est. primary completion 2030-12-31 · NCT07334301 · CT.gov ↗
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2031 (5)
February 2031 (1)
Phase 1/2Pediatric CancerRecruiting
Est. primary completion 2031-02 · NCT02813135 · CT.gov ↗
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March 2031 (2)
Phase 2/3High-Risk NeuroblastomaRecruiting
Est. primary completion 2031-03 · NCT07549321 · CT.gov ↗
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Phase 1/2Medulloblastoma, Medulloblastoma, Childhood, Medulloblastoma RecurrentRecruiting
Est. primary completion 2031-03-31 · NCT07346157 · CT.gov ↗
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December 2031 (2)
Phase 3GlioblastomaRecruiting
Est. primary completion 2031-12 · NCT07195591 · CT.gov ↗
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Phase 3Glioblastoma, IDH-wildtype, MGMT-Methylated GlioblastomaRecruiting
Est. primary completion 2031-12-15 · NCT06419946 · CT.gov ↗
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2032 (3)
June 2032 (2)
Phase 2Glioblastoma MultiformeRecruiting
Est. primary completion 2032-06 · NCT04765514 · CT.gov ↗
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Phase 1/2Glioblastoma, High-Grade Glioma (WHO III-IV), High-grade Glioma, Diffuse Midline Glioma, H3 K27M-Mutant, Diffuse Hemispheric Glioma …Not yet recruiting
Est. primary completion 2032-06-30 · NCT07389278 · CT.gov ↗
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December 2032 (1)
Phase 3GlioblastomaNot yet recruiting
Est. primary completion 2032-12-31 · NCT06477939 · CT.gov ↗
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2033 (1)
May 2033 (1)
Phase 3Astrocytoma, IDH-Mutant, Grade 3Recruiting
Est. primary completion 2033-05-31 · NCT07215910 · CT.gov ↗
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2034 (1)
October 2034 (1)
Phase 2RhabdomyosarcomaRecruiting
Est. primary completion 2034-10 · NCT06023641 · CT.gov ↗
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2035 (1)
June 2035 (1)
Phase 3Pancreatic Neuroendocrine Tumors (pNET), Pancreatic Neuroendocrine TumorsNot yet recruiting
Est. primary completion 2035-06 · NCT07591493 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (66)
Phase 2/3 (14)
Phase 2 (436)
Phase 1/2 (156)
Phase 1 (231)
Phase 4 (4)
Early phase / not applicable (26)
Used as active comparator (39)
Appears in other studies (30)