Asset profile

Synthetic hypericin

Small molecule

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Phase 3underway

Evidence outlook · registrational

Cutaneous T-Cell Lymphoma: registrational trials complete, results ungraded

Its supporting mid-stage evidence has not yet been graded on this platform. Its registrational studies have completed; results have not been graded on this platform. Check News and the registry record for topline outcomes.

Also in development:Psoriasis · Phase 2

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Competitive landscape

61 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 61 same-indication; 26 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Synthetic Hypericin: this drugPhase 3Small moleculePhotosensitizer (visible-light activated)
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Apremilast (Otezla)ApprovedSmall moleculePDE4
Bimekizumab (Bimzelx)ApprovedMonoclonal antibodyIL-17A/F
Brepocitinib (Lisraya)ApprovedSmall moleculeTYK2/JAK1
Brodalumab (Siliq)ApprovedMonoclonal antibodyIL-17 receptor A
Calcipotriene / Betamethasone Dipropionate Cream (Wynzora)ApprovedSmall moleculeVitamin D receptor + Glucocorticoid receptor
Calcipotriene / Betamethasone Dipropionate Foam (Enstilar)ApprovedSmall moleculeVitamin D receptor + Glucocorticoid receptor
Certolizumab Pegol (Cimzia)ApprovedAntibody fragmentTNF-alpha
Desoximetasone (Topicort Spray)ApprovedSmall moleculeGlucocorticoid receptor agonist
Deucravacitinib (Sotyktu)ApprovedSmall moleculeTYK2
Etanercept (Enbrel)ApprovedProtein / enzyme therapeuticTNF-alpha, TNF-alpha / TNF-beta (lymphotoxin-alpha)
Guselkumab (Tremfya)ApprovedMonoclonal antibodyIL-23 p19
Halobetasol Propionate Foam (Lexette)ApprovedSmall moleculeGlucocorticoid receptor
Halobetasol Propionate Lotion (Bryhali)ApprovedSmall moleculeGlucocorticoid receptor
Halobetasol Propionate / Tazarotene (Duobrii)ApprovedSmall moleculeGlucocorticoid receptor + retinoic acid receptor

…and 46 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 2 (4)
Phase 1 (2)